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KMID : 1031120140040020082
Journal of Epilepsy Research
2014 Volume.4 No. 2 p.82 ~ p.84
Valproic Acid-induced Hyperammonemic Encephalopathy Promoted by Levetiracetam
Roh Sook-Young

Jang Hyun-Soon
Jeong Eun-Hye
Kim Byung-Su
Sunwoo Moon-Kyung
Abstract
Encephalopathy resulting from the administration of levetiracetam (LEV) is a rare occurrence. We experienced a patient receiving LEV treated with valproic acid (VPA) for partial seizures with secondary generalization, following which she developed hyperammonemic encephalopathy and showed complete recovery after the drug was withdrawan. LEV is able to promote hyperammonemic encephalopathy when added to VPA.
KEYWORD
Valproic acid, Hyperammonemic encephalopathy, Levetiracetam
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